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Obesity is a multifactorial disorder influenced by genetic or environmental factors, and the incidence has tripled since 1975 as reported by the WHO (131)

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10.1172/JCI81203 123 LiY.ZhuL.ChenP.WangY.YangG.ZhouG.et al (2021)

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Therefore, determination of an accurate dosage coupled with guided patient stratification is key to the use of tivantinib as a target drug for HCC

Pathak R, Kumar A, Palfrey HA, Stone KP, Raju NR, Gettys TW, Murthy SN (2022) Prolonged effects of DPP-4 inhibitors on steato-hepatitic changes in Sprague-Dawley rats fed a high-cholesterol diet